SCHEMBL6939437

SCHEMBL6939437

CC(C)SCC[C@@H](N)C(O)C(=O)N(N)C(=O)C1CCOC1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 9/20 0.40
METAP1 P53582 8/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6477441 0.77 METAP2 (0.47) METAP2METAP1
SCHEMBL6563460 0.77 METAP2 (0.47) METAP2METAP1
SCHEMBL6935924 0.74 METAP2 (0.40) METAP2METAP1
SCHEMBL6941020 0.73 METAP2 (0.42) METAP2METAP1
SCHEMBL6935841 0.66 METAP2 (0.39) METAP2METAP1
SCHEMBL5849991 0.65 METAP2 (0.56) METAP2METAP1
SCHEMBL5848309 0.65 METAP2 (0.56) METAP2METAP1
SCHEMBL6245482 0.65 METAP2 (0.56) METAP2METAP1
SCHEMBL12989181 0.63 HSD17B10 (0.38)
SCHEMBL6563403 0.63 METAP2 (0.42) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1272456-A1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS Abbott Laboratories (US) 2003-01-08 EP claimed
WO-2001079157-A1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS ABBOTT LABORATORIES (US) 2001-10-25 WO claimed