Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573869 | 0.88 | GABRA1 (0.44) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL18566486 | 0.88 | PDE3B (0.41) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL2084784 | 0.86 | L3MBTL1 (0.50) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL19125435 | 0.86 | GABRA1 (0.42) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL2894516 | 0.86 | L3MBTL1 (0.46) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL23863915 | 0.86 | GABRA1 (0.42) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| Hydrochloric Acid SCHEMBL28470006 | 0.86 | PDE3B (0.41) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL12462038 | 0.85 | GABRA1 (0.41) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL12394751 | 0.85 | GABRA1 (0.41) | GABRA1GABRB2PDE3BPDE3ATRPM8 | |
| SCHEMBL27223876 | 0.83 | GABRA1 (0.36) | GABRA1GABRB2PDE3BPDE3ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707503-B2 | Modulators of complement activity | RA PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20180193408-A1 | MODULATORS OF COMPLEMENT ACTIVITY | UCB HOLDINGS, INC. | 2018-07-12 | — | — | US | disclosed |
| US-9937222-B2 | Modulators of complement activity | RA PHARMACEUTICALS, INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-20180021402-A1 | MODULATORS OF COMPLEMENT ACTIVITY | UCB HOLDINGS, INC. | 2018-01-25 | — | — | US | disclosed |
| US-20170137468-A1 | MODULATION OF COMPLEMENT ACTIVITY | UCB HOLDINGS, INC. | 2017-05-18 | — | — | US | disclosed |
| EP-0891970-B1 | Process for producing alkenylsubstituted pyridine derivatives | SUMITOMO CHEMICAL CO (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-6384175-B1 | WATER DISPERSIBLE; REACTION PRODUCT OF POLYETHER MODIFIED BY DIACID TO CONTAIN AT LEAST ONE ACID GROUP AND A LACQUER MONOMERIC POLYISOCYANATE ADDUCT; POLYURETHANES; CROSSLINKING AGENT FOR COATING BINDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-07 | — | — | US | disclosed |
| US-5075396-A | Coordination catalyst comprising magnesium, titanium, halogen, aluminum, an organosilicon compound and a heterocyclic diester as electron donor; durability; stereospecific | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-4841003-A | CCODINATION CATALYST CONTAINING MAGNESIUM, TITANIUM, HALOGEN, LEWIS BASE AND ORGANOALUMINUM COMPOUNDS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4725656-A | COORDINATION CATALYST COMPRISING MAGNESIUM TITANIUM, ALUMINUM, ORGANO SILICON COMPOUNDS, AND POLYESTERS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707503-B2 | Modulators of complement activity | C3AR1, C1QBP, C5AR1 | GABRA1 2777/4885GABRB2 2746/4885PDE3B 242/4885 |
| US-20180021402-A1 | MODULATORS OF COMPLEMENT ACTIVITY | C3AR1, C1QBP, C5AR1 | GABRA1 2777/4885GABRB2 2746/4885PDE3B 242/4885 |
| US-20170137468-A1 | MODULATION OF COMPLEMENT ACTIVITY | C5, C3AR1, CFH | GABRA1 3047/4885GABRB2 2904/4885PDE3B 500/4885 |
| US-20180193408-A1 | MODULATORS OF COMPLEMENT ACTIVITY | C3AR1, C1QBP, C5AR1 | GABRA1 2777/4885GABRB2 2746/4885PDE3B 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.