Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 9/20 | 0.46 |
| ▸ | LDHB | P07195 | 9/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918187 | 0.83 | LDHA (0.60) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL6920434 | 0.83 | MAPT (0.54) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL1045991 | 0.83 | SMN1; SMN2 (0.58) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL4199041 | 0.81 | HTT (0.47) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL5604635 | 0.80 | TSHR (0.49) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL28865452 | 0.80 | GAA (0.56) | HTTALDH1A1LMNAKMT2AGAA | |
| Bromide SCHEMBL7373319 | 0.78 | RAB9A (0.48) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL11669485 | 0.77 | LDHA (0.52) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL11669666 | 0.77 | LDHA (0.47) | HTTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL11671326 | 0.77 | LDHA (0.58) | HTTALDH1A1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |