Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 8/20 | 0.46 |
| ▸ | LDHB | P07195 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563493 | 0.83 | HTT (0.49) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL5918187 | 0.83 | LDHA (0.60) | MAPTKMT2AALDH1A1NPC1POLB | |
| SCHEMBL1045991 | 0.83 | SMN1; SMN2 (0.58) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL4199041 | 0.81 | HTT (0.47) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL5604635 | 0.80 | TSHR (0.49) | MAPTKMT2AALDH1A1LMNAHTT | |
| SCHEMBL28865452 | 0.80 | GAA (0.56) | MAPTKMT2AALDH1A1LMNAHTT | |
| Bromide SCHEMBL7373319 | 0.78 | RAB9A (0.48) | MAPTKMT2AALDH1A1NPC1POLB | |
| SCHEMBL11669666 | 0.77 | LDHA (0.47) | MAPTKMT2AALDH1A1NPC1LMNA | |
| SCHEMBL11669485 | 0.77 | LDHA (0.52) | MAPTKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL11671326 | 0.77 | LDHA (0.58) | MAPTKMT2AALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046141-A1 | NEW TRICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-06-03 | — | — | WO | disclosed |