Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565234 | 0.66 | SMN1; SMN2 (0.40) | KMT2AALDH1A1HSD17B10GAAL3MBTL1 | |
| SCHEMBL31134639 | 0.63 | KDM4E (0.42) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL10974939 | 0.63 | SMN1; SMN2 (0.46) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL21208575 | 0.62 | S1PR1 (0.38) | LMNA | |
| SCHEMBL14901973 | 0.61 | PTPN1 (0.43) | KMT2AALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL11357765 | 0.60 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL6340942 | 0.60 | TSHR (0.38) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL3207994 | 0.60 | LMNA (0.48) | KMT2AALDH1A1HSD17B10GAAL3MBTL1 | |
| SCHEMBL23291713 | 0.60 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL9674982 | 0.60 | TSHR (0.41) | KMT2AMEN1ALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |