SCHEMBL6563767

SCHEMBL6563767

NCCNc1ccc(OS(=O)(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.40
CA2 P00918 13/20 0.40
CA9 Q16790 13/20 0.40
CA1 P00915 12/20 0.40
CA12 O43570 11/20 0.40
PRSS1 P07477 1/20 0.36
EGFR P00533 2/20 0.36
ABL1 P00519 1/20 0.36
ABL2 P42684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8538458 0.78 MTNR1A (0.50) GAAGLAMAPTCA2CA9
Sulfuric Acid SCHEMBL6853065 0.77 ALDH1A1 (0.52) GAAMAPTCA2CA1CA12
SCHEMBL9800407 0.77 TSHR (0.47) CA2CA9CA1CA12
SCHEMBL3130086 0.76 CA2 (0.49) GAAGLACA2CA9CA1
SCHEMBL7128251 0.75 GAA (0.50) GAAMAPT
SCHEMBL7910581 0.74 GLA (0.53) GAAGLACA2CA9CA1
SCHEMBL18560960 0.73 TAAR1 (0.52) CA2CA9CA1CA12
Ammonia Solution, Strong SCHEMBL2908474 0.72 GLA (0.52) GAAGLACA2CA9CA1
SCHEMBL3381009 0.72 ALDH1A1 (0.55) GAAGLAMAPTCA2CA9
Ethylenediamine SCHEMBL11054948 0.72 CA1 (0.54) GAAGLACA2CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189993-B1 NOVEL DYES AND COLORANTS HENKEL KGAA (DE) 2004-02-18 EP disclosed