SCHEMBL6563917

SCHEMBL6563917

COc1ccc2nc(CCc3nc4ccc(OC)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.60
C1R P00736 2/20 0.55
ELANE P08246 2/20 0.50
ALDH1A1 P00352 6/20 0.49
MAPT P10636 5/20 0.49
HSD17B10 Q99714 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
LMNA P02545 3/20 0.49
POLB P06746 2/20 0.49
STAT1 P42224 1/20 0.49
CTSG P08311 2/20 0.48
KLK7 P49862 2/20 0.48
KLK14 Q9P0G3 2/20 0.48
KLK5 Q9Y337 2/20 0.48
CTRC Q99895 1/20 0.48
HTT P42858 1/20 0.47
HPGD P15428 4/20 0.46
F2 P00734 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098478 0.85 ELANE (0.63) KDM4EC1RELANEALDH1A1MAPT
SCHEMBL6563924 0.83 KMT2A (0.60) KDM4EELANEALDH1A1MAPTNPC1
SCHEMBL6567412 0.82 ELANE (0.50) KDM4EC1RELANEALDH1A1MAPT
SCHEMBL1820039 0.81 ELANE (0.66) KDM4EC1RELANEALDH1A1MAPT
SCHEMBL6565653 0.80 ELANE (0.68) KDM4EC1RELANEALDH1A1MAPT
SCHEMBL10340209 0.79 KDM4E (0.64) KDM4EC1RELANEALDH1A1MAPT
SCHEMBL2537004 0.79 MAPT (0.72) KDM4EC1RELANEALDH1A1MAPT
SCHEMBL6567413 0.78 KDM4E (0.54) KDM4EC1RALDH1A1MAPTHSD17B10
SCHEMBL6565945 0.77 ELANE (0.55) KDM4EELANEALDH1A1MAPTPOLB
SCHEMBL12927370 0.77 C1R (0.53) KDM4EC1RALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed