SCHEMBL6567412

SCHEMBL6567412

COc1ccc2nc(CC(C)c3nc4ccc(OC)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.50
C1R P00736 2/20 0.47
KDM4E B2RXH2 11/20 0.43
ALDH1A1 P00352 8/20 0.43
HTT P42858 2/20 0.43
MTNR1B P49286 1/20 0.43
HSD17B10 Q99714 4/20 0.41
MAPT P10636 4/20 0.41
LMNA P02545 3/20 0.41
CTSG P08311 2/20 0.41
KLK7 P49862 2/20 0.41
KLK14 Q9P0G3 2/20 0.41
KLK5 Q9Y337 2/20 0.41
CTRC Q99895 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
POLB P06746 2/20 0.41
STAT1 P42224 1/20 0.41
HPGD P15428 4/20 0.39
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566012 0.88 ELANE (0.48) ELANEKDM4EALDH1A1HTTHSD17B10
SCHEMBL6567154 0.86 KMT2A (0.52) ELANEKDM4EALDH1A1HTTHSD17B10
SCHEMBL6565609 0.84 ELANE (0.55) ELANEC1RKDM4EALDH1A1HTT
SCHEMBL6565331 0.82 ELANE (0.49) ELANEC1RKDM4EALDH1A1HTT
SCHEMBL6565211 0.82 ELANE (0.49) ELANEC1RKDM4EALDH1A1HTT
SCHEMBL6567394 0.82 ELANE (0.49) ELANEC1RKDM4EALDH1A1HTT
SCHEMBL6567158 0.82 ELANE (0.49) ELANEC1RKDM4EALDH1A1HTT
SCHEMBL6563917 0.82 KDM4E (0.60) ELANEC1RKDM4EALDH1A1HTT
SCHEMBL6565646 0.81 ELANE (0.48) ELANEKDM4EALDH1A1HTTMAPT
SCHEMBL6567413 0.81 KDM4E (0.54) C1RKDM4EALDH1A1HTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed