SCHEMBL6567413

SCHEMBL6567413

CCC(c1nc2ccc(OC)cc2c(=O)o1)c1nc2ccc(OC)cc2c(=O)o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.54
ALDH1A1 P00352 8/20 0.54
HTT P42858 2/20 0.54
C1R P00736 2/20 0.52
HSD17B10 Q99714 4/20 0.46
LMNA P02545 3/20 0.46
MAPT P10636 6/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
POLB P06746 2/20 0.46
STAT1 P42224 1/20 0.46
CTSG P08311 2/20 0.45
KLK7 P49862 2/20 0.45
KLK14 Q9P0G3 2/20 0.45
KLK5 Q9Y337 2/20 0.45
CTRC Q99895 1/20 0.45
HPGD P15428 5/20 0.43
F2 P00734 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566018 0.88 SMN1; SMN2 (0.48) KDM4EALDH1A1HTTHSD17B10LMNA
SCHEMBL6567157 0.84 KMT2A (0.57) KDM4EALDH1A1HTTHSD17B10LMNA
SCHEMBL6565611 0.81 ELANE (0.62) KDM4EALDH1A1HTTC1RLMNA
SCHEMBL6567412 0.81 ELANE (0.50) KDM4EALDH1A1HTTC1RHSD17B10
SCHEMBL6567397 0.80 ALDH1A1 (0.48) KDM4EALDH1A1HTTC1RLMNA
SCHEMBL6567161 0.80 TP53 (0.51) KDM4EALDH1A1HTTMAPTNPC1
SCHEMBL6565648 0.80 ELANE (0.48) KDM4EALDH1A1HTTLMNAMAPT
SCHEMBL6565334 0.80 KDM4E (0.47) KDM4EALDH1A1HTTC1R
SCHEMBL6565217 0.80 MAPT (0.47) KDM4EALDH1A1HTTHSD17B10MAPT
SCHEMBL6563917 0.78 KDM4E (0.60) KDM4EALDH1A1HTTC1RHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed