SCHEMBL6565945

SCHEMBL6565945

CCc1ccc2nc(CCc3nc4ccc(CC)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.55
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HPN P05981 1/20 0.42
TYMS P04818 1/20 0.42
MAPT P10636 1/20 0.41
PDE10A Q9Y233 1/20 0.41
GAA P10253 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6563931 0.89 ELANE (0.61) ELANEKDM4EMEN1KMT2AHPN
SCHEMBL6565646 0.81 ELANE (0.48) ELANEKDM4EMEN1KMT2AHPN
SCHEMBL6565653 0.81 ELANE (0.68) ELANEKDM4EMEN1KMT2AMAPT
SCHEMBL6563910 0.80 HPN (0.56) ELANEKDM4EMEN1KMT2AHPN
SCHEMBL6565648 0.79 ELANE (0.48) ELANEKDM4EMEN1KMT2AHPN
SCHEMBL6567409 0.78 ELANE (0.50) ELANEKDM4EMEN1KMT2ATYMS
SCHEMBL6565207 0.78 C1R (0.52) ELANEKDM4EMEN1KMT2AMAPT
SCHEMBL6565727 0.78 KDM4E (0.52) ELANEKDM4EMEN1KMT2AMAPT
SCHEMBL6567186 0.78 ELANE (0.50) ELANEKDM4EMEN1KMT2AMAPT
SCHEMBL6563917 0.77 KDM4E (0.60) ELANEKDM4EKMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed