SCHEMBL6563950

SCHEMBL6563950

O=c1oc(-c2ccc3cc(-c4nc5ccc(Cl)cc5c(=O)o4)ccc3c2)nc2ccc(Cl)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
KDM4E B2RXH2 5/20 0.59
C1R P00736 2/20 0.59
APEX1 P27695 2/20 0.50
HPN P05981 1/20 0.50
MAPT P10636 4/20 0.48
HSD17B10 Q99714 2/20 0.48
ELANE P08246 1/20 0.47
RAB9A P51151 4/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TP53 P04637 1/20 0.46
NPC1 O15118 4/20 0.46
HPGD P15428 4/20 0.46
F2 P00734 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
PTGES O14684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328301 0.92 ALDH1A1 (0.63) ALDH1A1KDM4EC1RAPEX1HPN
SCHEMBL6565952 0.88 APEX1 (0.59) ALDH1A1KDM4EC1RAPEX1MAPT
SCHEMBL2704120 0.86 C1R (0.68) ALDH1A1KDM4EC1RAPEX1HPN
SCHEMBL14417720 0.82 ALDH1A1 (0.66) ALDH1A1KDM4EC1RAPEX1MAPT
SCHEMBL6564042 0.82 MAPT (0.48) ALDH1A1KDM4EC1RHPNMAPT
SCHEMBL6565595 0.82 TP53 (0.65) ALDH1A1KDM4EHPNMAPTHSD17B10
SCHEMBL6567424 0.82 ELANE (0.62) ALDH1A1KDM4EC1RHPNMAPT
SCHEMBL6565915 0.82 MAPT (0.68) ALDH1A1KDM4EHPNMAPTHSD17B10
SCHEMBL757083 0.80 ELANE (0.75) ALDH1A1KDM4EMAPTHSD17B10ELANE
SCHEMBL30423811 0.80 ELANE (0.75) ALDH1A1KDM4EMAPTHSD17B10ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed