SCHEMBL757083

SCHEMBL757083

O=c1oc(-c2ccc3cc(-c4nc5ccccc5c(=O)o4)ccc3c2)nc2ccccc12

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.75
NPC1 O15118 5/20 0.69
RAB9A P51151 4/20 0.69
RXFP1 Q9HBX9 1/20 0.69
ALDH1A1 P00352 8/20 0.68
MAPT P10636 6/20 0.68
KDM4E B2RXH2 5/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
LMNA P02545 2/20 0.68
KMT2A Q03164 7/20 0.68
HPGD P15428 3/20 0.68
F2 P00734 2/20 0.68
TP53 P04637 4/20 0.63
MEN1 O00255 6/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
HSD17B10 Q99714 1/20 0.60
MAPK10 P53779 1/20 0.58
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423811 1.00 ELANE (0.75) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL1532720 0.97 ELANE (0.71) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL31329230 0.97 ELANE (0.71) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL125184 0.90 ELANE (0.93) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL29456973 0.90 ELANE (0.93) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL272872 0.88 ELANE (0.83) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL3254378 0.88 ELANE (0.89) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL271965 0.88 ELANE (0.83) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL29444225 0.88 ELANE (0.83) ELANENPC1RAB9ARXFP1ALDH1A1
SCHEMBL12212888 0.88 ELANE (0.89) ELANENPC1RAB9ARXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
US-12242095-B2 Optical film, polarizing plate, surface plate for image display device, and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2025-03-04 US disclosed
WO-2023190740-A1 OUTER ATTACHMENT WINDOW FILM リンテック株式会社 2023-10-05 WO disclosed
US-20210405272-A1 OPTICAL FILM, POLARIZING PLATE, SURFACE PLATE FOR IMAGE DISPLAY DEVICE, AND IMAGE DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2021-12-30 US disclosed
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER L'OREAL (FR) 2021-11-11 US disclosed
CN-113272689-A Optical film, polarizing plate, surface plate for image display device, and image display device 大日本印刷株式会社 2021-08-17 CN disclosed
EP-2872107-B1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES OREAL (FR) 2021-07-21 EP disclosed
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'OREAL (FR) 2020-11-19 US disclosed
CN-108780169-B Light source unit, laminated member, and display and lighting device using the same 东丽株式会社 2020-06-05 CN disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP disclosed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US disclosed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP disclosed
EP-0383941-B1 ULTRAVIOLET ABSORBING COSMETIC TEIJIN LTD (JP) 1993-11-03 EP disclosed
US-5234681-A A phenylene-, naphthylene- or biphenylenebis(3,1-benzoxazin-4-one; sunscreen agents; colorless, odorless and nonirritating; durability TEIJIN LIMITED (JP) 1993-08-10 US disclosed
EP-0383941-A1 ULTRAVIOLET ABSORBING COSMETIC TEIJIN LIMITED (JP) 1990-08-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT PCNA, ERCC1, XRCC6 ELANE 144/4885NPC1 1496/4885RAB9A 3199/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD ELANE 4186/4885NPC1 2529/4885RAB9A 4067/4885
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER ERCC5, CUTA, PLIN5 ELANE 688/4885NPC1 3005/4885RAB9A 3649/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 ELANE 4388/4885NPC1 3007/4885RAB9A 4526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.