Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008825 | 0.92 | ALDH1A1 (0.51) | SLC6A4EPHX2KDM1AGRIN2BALDH1A1 | |
| SCHEMBL6161958 | 0.86 | ALDH1A1 (0.47) | SLC6A4LTA4HEPHX2ALDH1A1TSHR | |
| SCHEMBL3602312 | 0.86 | ALDH1A1 (0.47) | SLC6A4ALDH1A1TSHRKIF11CHRM5 | |
| SCHEMBL31374891 | 0.81 | CHRM5 (0.48) | LTA4HEPHX2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27862141 | 0.81 | KIF11 (0.47) | SLC6A4LTA4HEPHX2KDM1AGRIN2B | |
| SCHEMBL168125 | 0.81 | KIF11 (0.47) | SLC6A4LTA4HEPHX2KDM1AGRIN2B | |
| SCHEMBL16770891 | 0.80 | SLC6A4 (0.58) | SLC6A4LTA4HEPHX2KDM1AGRIN2B | |
| SCHEMBL4380372 | 0.79 | MRGPRX4 (0.57) | BCHEMAPTSMN1; SMN2 | |
| SCHEMBL29087324 | 0.79 | KIF11 (0.46) | SLC6A4LTA4HEPHX2KDM1AGRIN2B | |
| Ammonia Solution, Strong SCHEMBL2163079 | 0.79 | KIF11 (0.46) | SLC6A4LTA4HEPHX2KDM1AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219591-B1 | Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine | BAYER CHEMICALS AG (DE) | 2004-03-31 | — | — | EP | disclosed |
| EP-1219591-A1 | Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine and 4-bromomethyl- and 4-chloromethyl- -1trifluoromethoxybenzene | Bayer Aktiengesellschaft (DE) | 2002-07-03 | — | — | EP | disclosed |