SCHEMBL6563997

SCHEMBL6563997

CCc1ccc2nc(C3CCCCC3c3nc4ccc(CC)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.44
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
POLB P06746 2/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HPN P05981 1/20 0.38
TYMS P04818 1/20 0.37
LMNA P02545 1/20 0.36
TRPC5 Q9UL62 1/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
RAD52 P43351 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566030 0.82 ELANE (0.59) ELANEALDH1A1POLBL3MBTL1LMNA
SCHEMBL6565228 0.81 SMN1; SMN2 (0.45) ELANEALDH1A1TSHRPOLBL3MBTL1
SCHEMBL6566025 0.80 ATM (0.37) ELANEALDH1A1POLBL3MBTL1GAA
SCHEMBL6567166 0.80 ELANE (0.38) ELANETYMS
SCHEMBL6565946 0.80 ALDH1A1 (0.47) ELANEALDH1A1POLBMAPK1HPGD
SCHEMBL6565060 0.80 C1R (0.47) ELANEALDH1A1POLBL3MBTL1HSD17B10
SCHEMBL6564006 0.79 C1R (0.50) ALDH1A1TSHRPOLBHPGDHSD17B10
SCHEMBL6564167 0.78 ALDH1A1 (0.40) ELANEALDH1A1POLBL3MBTL1GAA
SCHEMBL6564024 0.77 IP6K1 (0.41) ELANEALDH1A1POLBL3MBTL1GAA
SCHEMBL6564050 0.75 RAB9A (0.52) ELANEALDH1A1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed