SCHEMBL6566030

SCHEMBL6566030

Cc1ccc2nc(C3CCCCC3c3nc4ccc(C)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.59
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
POLB P06746 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PTK2B Q14289 1/20 0.48
C1R P00736 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
GABRP O00591 2/20 0.40
GABRD O14764 2/20 0.40
GABRA1 P14867 2/20 0.40
GABRB1 P18505 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565946 0.83 ALDH1A1 (0.47) ELANEKDM4EALDH1A1POLBMEN1
SCHEMBL6565060 0.83 C1R (0.47) ELANEKDM4EALDH1A1POLBC1R
SCHEMBL6567166 0.83 ELANE (0.38) ELANEC1R
SCHEMBL6563997 0.82 ELANE (0.44) ELANEALDH1A1POLBMEN1KMT2A
SCHEMBL6564006 0.82 C1R (0.50) KDM4EALDH1A1POLBKMT2AC1R
SCHEMBL6564167 0.81 ALDH1A1 (0.40) ELANEKDM4EALDH1A1POLBMEN1
SCHEMBL6564024 0.81 IP6K1 (0.41) ELANEKDM4EALDH1A1POLBMEN1
SCHEMBL6565228 0.79 SMN1; SMN2 (0.45) ELANEKDM4EALDH1A1POLBMEN1
SCHEMBL6564050 0.79 RAB9A (0.52) ELANEALDH1A1MEN1KMT2AC1R
SCHEMBL6566025 0.78 ATM (0.37) ELANEKDM4EALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed