Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547930 | 0.92 | MAPT (0.37) | MAPTTHRBRARBRARAKMT2A | |
| SCHEMBL6547169 | 0.90 | ALDH1A1 (0.40) | MAPTKMT2APRSS1TMPRSS15 | |
| SCHEMBL6564025 | 0.87 | MAPT (0.52) | MAPTTHRBSMN1; SMN2SENP8SENP7 | |
| SCHEMBL6562379 | 0.87 | MAPT (0.52) | MAPTTHRBSMN1; SMN2SENP8SENP7 | |
| SCHEMBL6563804 | 0.84 | KMT2A (0.37) | MAPTRAB9AKMT2APRSS1TMPRSS15 | |
| SCHEMBL6562073 | 0.82 | CYP4F2 (0.48) | MAPTTHRBSMN1; SMN2RARBRARA | |
| SCHEMBL6563854 | 0.81 | MAPT (0.47) | MAPTTHRBSMN1; SMN2NPC1RARB | |
| SCHEMBL6560933 | 0.80 | MAPT (0.52) | MAPTTHRBSMN1; SMN2NPC1RARB | |
| SCHEMBL6562354 | 0.79 | RARB (0.41) | MAPTSMN1; SMN2NPC1RAB9ARARB | |
| SCHEMBL6561998 | 0.79 | TP53 (0.46) | MAPTTHRBSMN1; SMN2KMT2APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |