Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MMP15 | P51511 | 1/20 | 0.36 |
| ▸ | MMP16 | P51512 | 1/20 | 0.36 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561426 | 0.80 | MAPT (0.41) | MAPTFFAR1NPC1RAB9ANPSR1 | |
| SCHEMBL6561387 | 0.80 | FFAR1 (0.40) | MAPTFFAR1NPC1RAB9ANPSR1 | |
| SCHEMBL6562542 | 0.75 | KCNN4 (0.37) | MAPTFFAR1NPC1RAB9ANPSR1 | |
| SCHEMBL6562626 | 0.73 | MAPT (0.40) | GAAMAPTFFAR1HTTNPC1 | |
| Diphenylacetylene SCHEMBL27967498 | 0.71 | APP (0.52) | MAPTFFAR1HTTNPC1RAB9A | |
| SCHEMBL28927133 | 0.70 | FFAR1 (0.43) | GAAMAPTFFAR1HTTNPC1 | |
| SCHEMBL6562562 | 0.70 | MAPT (0.38) | GAAMAPTFFAR1HTTNPC1 | |
| SCHEMBL10729135 | 0.70 | GAA (0.48) | GAAMAPTFFAR1NPSR1ALDH1A1 | |
| SCHEMBL9135241 | 0.70 | MAPT (0.51) | MAPTFFAR1HTTNPC1RAB9A | |
| SCHEMBL28927161 | 0.69 | MAPT (0.51) | MAPTFFAR1NPSR1PAMMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122746-B1 | Composition for film formation and insulating film | JSR CORP (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6468589-B2 | A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING | JSR CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20010012870-A1 | Composition for film formation and insulating film | JSR CORPORATION (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1122746-A1 | Composition for film formation and insulating film | JSR Corporation (JP) | 2001-08-08 | — | — | EP | disclosed |