Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.52 |
| ▸ | RXRB | P28702 | 4/20 | 0.52 |
| ▸ | RXRG | P48443 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889062 | 0.93 | RAB9A (0.54) | RXRARXRBRXRGKDM4EMRGPRX4 | |
| SCHEMBL6562731 | 0.88 | MRGPRX4 (0.48) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL6566454 | 0.87 | MRGPRX4 (0.47) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL6886989 | 0.83 | MAPT (0.53) | RXRARXRBRXRGKDM4EMRGPRX4 | |
| SCHEMBL6565076 | 0.82 | MRGPRX4 (0.47) | RXRARXRBRXRGMRGPRX4RAB9A | |
| SCHEMBL6889652 | 0.82 | RAB9A (0.52) | RXRARXRBRXRGKDM4EMRGPRX4 | |
| SCHEMBL6562778 | 0.80 | NR1H4 (0.48) | RXRARXRBMRGPRX4RAB9AL3MBTL1 | |
| SCHEMBL6566172 | 0.79 | MRGPRX4 (0.63) | RXRARXRBRXRGMRGPRX4RAB9A | |
| SCHEMBL6564818 | 0.77 | MRGPRX4 (0.54) | MRGPRX4 | |
| SCHEMBL6888088 | 0.76 | PPARG (0.46) | MRGPRX4MAPTL3MBTL1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |