Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564136 | 0.93 | RXRA (0.52) | RAB9AMAPTLMNAL3MBTL1NPC1 | |
| SCHEMBL6886989 | 0.90 | MAPT (0.53) | RAB9AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6889652 | 0.89 | RAB9A (0.52) | RAB9AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6562731 | 0.83 | MRGPRX4 (0.48) | RAB9AMAPTLMNAL3MBTL1NPC1 | |
| SCHEMBL6566454 | 0.82 | MRGPRX4 (0.47) | RAB9AMAPTLMNAL3MBTL1NPC1 | |
| SCHEMBL6882624 | 0.82 | SMN1; SMN2 (0.45) | RAB9AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6882555 | 0.81 | MRGPRX4 (0.55) | RAB9AMAPTALDH1A1NPC1GAA | |
| SCHEMBL6888101 | 0.78 | MRGPRX4 (0.47) | RAB9AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6883847 | 0.77 | MRGPRX4 (0.47) | RAB9AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6890556 | 0.76 | NR1H2 (0.47) | SMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |