Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564955 | 0.89 | VDR (0.38) | VDRPDK2MAOBPDK1PDK3 | |
| SCHEMBL6564984 | 0.85 | VDR (0.39) | VDRPDK2 | |
| SCHEMBL6564186 | 0.85 | VDR (0.35) | VDRPDK2 | |
| SCHEMBL6564512 | 0.84 | VDR (0.35) | VDRPDK2 | |
| SCHEMBL6889710 | 0.81 | VDR (0.41) | VDRPDK2MAOBPDK1PDK3 | |
| SCHEMBL6564553 | 0.81 | VDR (0.39) | VDRPDK2MAOBPDK1PDK3 | |
| SCHEMBL6564961 | 0.78 | VDR (0.38) | VDRPDK2MAOB | |
| SCHEMBL6564896 | 0.75 | VDR (0.34) | VDRPDK2 | |
| SCHEMBL7638648 | 0.74 | VDR (0.40) | VDR | |
| SCHEMBL6564946 | 0.74 | VDR (0.39) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |