Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564553 | 0.92 | VDR (0.39) | VDRPPARGPPARDPPARAPDK2 | |
| SCHEMBL7638648 | 0.84 | VDR (0.40) | VDR | |
| SCHEMBL6564961 | 0.83 | VDR (0.38) | VDRPPARGPPARDPPARAPDK2 | |
| SCHEMBL6564550 | 0.81 | VDR (0.39) | VDRPDK2PDK1PDK3PDK4 | |
| SCHEMBL6564955 | 0.79 | VDR (0.38) | VDRPPARGPPARDPPARAPDK2 | |
| SCHEMBL6564597 | 0.77 | VDR (0.61) | VDRPPARGPPARDPPARAMAOB | |
| SCHEMBL6564989 | 0.76 | VDR (0.40) | VDR | |
| SCHEMBL6564520 | 0.75 | VDR (0.35) | VDRPDK2PDCD1CD274 | |
| SCHEMBL7612371 | 0.74 | VDR (0.43) | VDRPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6564145 | 0.73 | VDR (0.55) | VDRPPARGPPARDPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |