⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149840 | 0.83 | — | — | |
| SCHEMBL12315103 | 0.80 | ALDH1A1 (0.60) | — | |
| SCHEMBL187616 | 0.80 | — | — | |
| SCHEMBL28404629 | 0.80 | ALDH1A1 (0.60) | — | |
| SCHEMBL291550 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL1111518 | 0.78 | — | — | |
| SCHEMBL2984393 | 0.76 | ALDH1A1 (0.55) | — | |
| SCHEMBL644043 | 0.76 | — | — | |
| SCHEMBL2986945 | 0.76 | ALDH1A1 (0.55) | — | |
| SCHEMBL21983314 | 0.76 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889929-A | ESTERIFICATION OF BENZYL PENICILLIN OR SALT WITH 1-BROMOETHYL ETHYL CARBONATE | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1989-12-26 | — | — | US | claimed |
| EP-0108547-B1 | PROCESS FOR THE PREPARATION OF THE 1'-ETHOXYCARBONYLOXYETHYL ESTER OF BENZYLPENICILLIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1989-06-07 | — | — | EP | claimed |
| EP-0112130-B1 | ETHOXYCARBONYLOXY ETHYL ESTERS OF NON-STEROIDAL ANTI-INFLAMMATORY CARBOXYLIC ACIDS, THEIR PREPARATION AND USE | Teva Pharmaceutical Industries Limited (IL) | 1987-03-04 | — | — | EP | claimed |
| EP-0114720-B1 | 1'-ETHOXYCARBONYLOXYETHYL ESTER OF VALPROIC ACID, ITS PREPARATION AND FORMULATIONS CONTAINING IT | Teva Pharmaceutical Industries Limited (IL) | 1986-02-26 | — | — | EP | claimed |
| EP-0114720-A1 | 1'-Ethoxycarbonyloxyethyl ester of valproic acid, its preparation and formulations containing it | Teva Pharmaceutical Industries Limited (IL) | 1984-08-01 | — | — | EP | claimed |
| EP-0112130-A1 | Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids, their preparation and use | Teva Pharmaceutical Industries Limited (IL) | 1984-06-27 | — | — | EP | claimed |
| EP-0108547-A2 | Process for the preparation of the 1'-ethoxycarbonyloxyethyl ester of benzylpenicillin | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1984-05-16 | — | — | EP | claimed |
| WO-2016055901-A1 | SUBSTITUTED AMIDE COMPOUNDS | PFIZER INC. (US) | 2016-04-14 | — | — | WO | disclosed |
| US-20160102074-A1 | SUBSTITUTED AMIDE COMPOUNDS | PFIZER INC. (US) | 2016-04-14 | — | — | US | disclosed |
| EP-0981958-B1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEM RES (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6548511-B1 | Anilinopyrimidinone derivatives of given formula such as 2-(2,5-bis(trifluoromethyl)phenyl)amino-5-chloro-3-isobutyl-6 -trifluoromethyl-4(3H)-pyrimidinone; controlling pests of agricultural and horticultural products | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-0981958-A1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-03-01 | — | — | EP | disclosed |
| WO-1994015904-A1 | NOVEL PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PRODRUGS | PHARMACIA AB (SE) | 1994-07-21 | — | — | WO | disclosed |
| EP-0114720-B1 | 1'-ETHOXYCARBONYLOXYETHYL ESTER OF VALPROIC ACID, ITS PREPARATION AND FORMULATIONS CONTAINING IT | Teva Pharmaceutical Industries Limited (IL) | 1986-02-26 | — | — | EP | disclosed |
| US-4560683-A | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1985-12-24 | — | — | US | disclosed |
| EP-0150458-A2 | Cephem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1985-08-07 | — | — | EP | disclosed |
| EP-0114720-A1 | 1'-Ethoxycarbonyloxyethyl ester of valproic acid, its preparation and formulations containing it | Teva Pharmaceutical Industries Limited (IL) | 1984-08-01 | — | — | EP | disclosed |
| EP-0112130-A1 | Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids, their preparation and use | Teva Pharmaceutical Industries Limited (IL) | 1984-06-27 | — | — | EP | disclosed |
| EP-0108547-A2 | Process for the preparation of the 1'-ethoxycarbonyloxyethyl ester of benzylpenicillin | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1984-05-16 | — | — | EP | disclosed |
| EP-0108547-A2 | Process for the preparation of the 1'-ethoxycarbonyloxyethyl ester of benzylpenicillin | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1984-05-16 | — | — | EP | disclosed |