SCHEMBL6564819

SCHEMBL6564819

CCC(=O)c1cc(CCc2ccc(C(C)(C)O[SiH2]C(C)(C)C)c(C(C)(C)O[SiH2]C(C)(C)C)c2)cs1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.36
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6563989 0.84 POLB (0.43) HPGD
SCHEMBL6562928 0.84 DAO (0.31) DAO
SCHEMBL6566330 0.83
SCHEMBL6563074 0.82 DAO (0.33) DAO
SCHEMBL6566249 0.79 VDR (0.34)
SCHEMBL6566200 0.78
SCHEMBL6156234 0.73 MAOB (0.39)
SCHEMBL6623024 0.72 MEN1 (0.35)
SCHEMBL3280119 0.71 PDPK1 (0.36)
SCHEMBL6562965 0.70 DAO (0.43) DAOHPGDHTTMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235824-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-05-19 EP disclosed