Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 18/20 | 0.66 |
| ▸ | METAP1 | P53582 | 10/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563175 | 0.86 | METAP2 (0.62) | METAP2METAP1ATM | |
| SCHEMBL6488594 | 0.79 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6563362 | 0.79 | METAP2 (0.62) | METAP2METAP1 | |
| SCHEMBL6485546 | 0.78 | METAP2 (0.67) | METAP2METAP1 | |
| SCHEMBL6563062 | 0.74 | METAP2 (0.66) | METAP2METAP1 | |
| SCHEMBL6487894 | 0.71 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6477544 | 0.70 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6477126 | 0.69 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL7320581 | 0.68 | METAP2 (0.68) | METAP2METAP1 | |
| SCHEMBL6476924 | 0.67 | METAP2 (0.63) | METAP2METAP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |