SCHEMBL6565171

SCHEMBL6565171

CCN(C(C)C)C(C)C.NC(=S)S

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.40
CYP2E1 P05181 1/20 0.40
PTGS1 P23219 1/20 0.40
HTT P42858 1/20 0.40
GSDMD P57764 1/20 0.40
ALDH1A1 P00352 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL22492307 0.90 TSHR (0.33) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL6565177 0.87 MEN1 (0.31) ABCB11CYP2E1PTGS1HTTGSDMD
Ditiocarb SCHEMBL3140725 0.81 ABCB11 (0.68) ABCB11CYP2E1PTGS1HTTGSDMD
Methyl Alcohol SCHEMBL2652388 0.78 MEN1 (0.38)
SCHEMBL7097725 0.78
SCHEMBL5544690 0.78 MEN1 (0.42)
SCHEMBL1746 0.78
Carbamic Acid SCHEMBL28872525 0.77 ACHE (0.37)
Ethylamine SCHEMBL8329983 0.75 MEN1 (0.36) ALDH1A1
Alcohol SCHEMBL28322766 0.75 TSHR (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377546-A2 PROCESS FOR PRODUCING THIOSEMICARBAZIDES Dow AgroSciences LLC (US) 2004-01-07 EP claimed
WO-2002081438-A2 PROCESS FOR PRODUCING THIOSEMICARBAZIDES DOW AGROSCIENCES LCC (US) 2002-10-17 WO claimed
WO-1998037074-A1 PROCESS FOR PREPARATION OF 2-MERCAPTOTHIAZOLE ZENECA LIMITED (GB) 1998-08-27 WO claimed
EP-1377546-A2 PROCESS FOR PRODUCING THIOSEMICARBAZIDES Dow AgroSciences LLC (US) 2004-01-07 EP disclosed
WO-2002081438-A2 PROCESS FOR PRODUCING THIOSEMICARBAZIDES DOW AGROSCIENCES LCC (US) 2002-10-17 WO disclosed
WO-1998037074-A1 PROCESS FOR PREPARATION OF 2-MERCAPTOTHIAZOLE ZENECA LIMITED (GB) 1998-08-27 WO disclosed