Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GSDMD | P57764 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565177 | 0.92 | MEN1 (0.31) | EHMT2EHMT1KMT2AABCB11HTT | |
| SCHEMBL6565171 | 0.90 | ABCB11 (0.40) | ABCB11HTTGSDMDCYP2E1PTGS1 | |
| Methyl Alcohol SCHEMBL2652388 | 0.82 | MEN1 (0.38) | TSHRKMT2AMEN1 | |
| SCHEMBL7097725 | 0.82 | — | — | |
| SCHEMBL5544690 | 0.82 | MEN1 (0.42) | KMT2AMEN1 | |
| SCHEMBL1746 | 0.82 | — | — | |
| Carbamic Acid SCHEMBL28872525 | 0.81 | ACHE (0.37) | ADRA2AADRA2BACHE | |
| Ethylamine SCHEMBL8329983 | 0.79 | MEN1 (0.36) | KMT2AMEN1ALDH1A1 | |
| Alcohol SCHEMBL28322766 | 0.79 | TSHR (0.40) | TSHRKMT2AMEN1ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL28105402 | 0.79 | ALDH1A1 (0.40) | TSHRKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3719125-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, AND PREPARATION METHOD AND USE | Suzhou Ribo Life Science Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |