Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764579 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL27623118 | 0.64 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ECYP1A2PTPN1 | |
| SCHEMBL6571937 | 0.64 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1MAPTKDM4EL3MBTL1 | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.63 | GAA (0.67) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.63 | GAA (0.67) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT | |
| SCHEMBL14409745 | 0.62 | TSHR (0.50) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT | |
| SCHEMBL1027353 | 0.62 | PPARG (0.36) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT | |
| Succinic Acid Diethyl Ester SCHEMBL29494609 | 0.61 | GAA (0.63) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT | |
| Succinic Acid Diethyl Ester SCHEMBL21815758 | 0.61 | GAA (0.63) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT | |
| Succinic Acid Diethyl Ester SCHEMBL4324913 | 0.61 | GAA (0.63) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |