Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573962 | 0.79 | NPC1 (0.49) | SMN1; SMN2L3MBTL1HSD17B10KMT2ANPC1 | |
| SCHEMBL6565369 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL691909 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2TRPM8ALDH1A1L3MBTL1LMNA | |
| SCHEMBL1140947 | 0.67 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL9324850 | 0.67 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL23513252 | 0.66 | SMN1; SMN2 (0.51) | SMN1; SMN2TRPM8ALDH1A1L3MBTL1LMNA | |
| SCHEMBL13086854 | 0.66 | SMN1; SMN2 (0.51) | SMN1; SMN2TRPM8ALDH1A1L3MBTL1LMNA | |
| SCHEMBL27493267 | 0.66 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL1303146 | 0.66 | LTA4H (0.62) | SMN1; SMN2ALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL10500044 | 0.65 | ALOX5 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | SMN1; SMN2 2628/4885TRPM8 2746/4885ALDH1A1 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.