SCHEMBL6565623

SCHEMBL6565623

CCC(=O)c1ccc2nc(CC(C)c3nc4ccc(C(=O)CC)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.44
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 3/20 0.34
SLC27A1 Q6PCB7 1/20 0.34
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567552 0.88 ELANE (0.46) ELANEKDM4EALDH1A1HTTLMNA
SCHEMBL6565631 0.83 KDM4E (0.43) ELANEKDM4EALDH1A1HTTLMNA
SCHEMBL6566008 0.83 ELANE (0.50) ELANEKDM4ELMNASLC27A1MEN1
SCHEMBL6565211 0.82 ELANE (0.49) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565646 0.81 ELANE (0.48) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565609 0.81 ELANE (0.55) ELANEKDM4EALDH1A1HTTLMNA
SCHEMBL6565331 0.80 ELANE (0.49) ELANEKDM4EALDH1A1HTTLMNA
SCHEMBL6567394 0.80 ELANE (0.49) ELANEKDM4EALDH1A1HTTLMNA
SCHEMBL6567158 0.80 ELANE (0.49) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565061 0.79 ELANE (0.47) ELANEKDM4EALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed