SCHEMBL6567394

SCHEMBL6567394

CC(Cc1nc2ccc(Cl)cc2c(=O)o1)c1nc2ccc(Cl)cc2c(=O)o1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.49
C1R P00736 4/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
FABP3 P05413 1/20 0.34
FABP4 P15090 1/20 0.34
FABP5 Q01469 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566275 0.90 ELANE (0.49) ELANEC1RALDH1A1KDM4ELMNA
SCHEMBL6565609 0.86 ELANE (0.55) ELANEC1RALDH1A1KDM4ELMNA
SCHEMBL6567158 0.85 ELANE (0.49) ELANEC1RALDH1A1KDM4EHTT
SCHEMBL6565331 0.85 ELANE (0.49) ELANEC1RALDH1A1KDM4ELMNA
SCHEMBL6565211 0.85 ELANE (0.49) ELANEC1RALDH1A1KDM4EHTT
SCHEMBL6353490 0.84 ELANE (0.51) ELANEC1RALDH1A1KDM4ELMNA
SCHEMBL6565646 0.84 ELANE (0.48) ELANEALDH1A1KDM4EHTTMEN1
SCHEMBL6567412 0.82 ELANE (0.50) ELANEC1RALDH1A1KDM4ELMNA
SCHEMBL3817466 0.82 C1R (0.53) ELANEC1RALDH1A1KDM4ELMNA
SCHEMBL6567552 0.81 ELANE (0.46) ELANEALDH1A1KDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed