SCHEMBL6567552

SCHEMBL6567552

CC(=O)c1ccc2nc(CC(C)c3nc4ccc(C(C)=O)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.46
KDM4E B2RXH2 6/20 0.38
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
SLC2A1 P11166 1/20 0.38
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
HTT P42858 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565623 0.88 ELANE (0.44) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6565211 0.84 ELANE (0.49) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6567154 0.83 KMT2A (0.52) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6565609 0.83 ELANE (0.55) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6565072 0.82 KDM4E (0.49) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6565331 0.81 ELANE (0.49) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6567158 0.81 ELANE (0.49) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6567394 0.81 ELANE (0.49) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6567556 0.81 ELANE (0.44) ELANEKDM4EALDH1A1MEN1KMT2A
SCHEMBL6565646 0.81 ELANE (0.48) ELANEKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed