SCHEMBL6565646

SCHEMBL6565646

CCc1ccc2nc(CC(C)c3nc4ccc(CC)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.48
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HPN P05981 1/20 0.36
TYMS P04818 1/20 0.36
MAPT P10636 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565061 0.90 ELANE (0.47) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565609 0.85 ELANE (0.55) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565331 0.84 ELANE (0.49) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6567394 0.84 ELANE (0.49) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565211 0.84 ELANE (0.49) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6567158 0.84 ELANE (0.49) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6566012 0.82 ELANE (0.48) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6567412 0.81 ELANE (0.50) ELANEKDM4EALDH1A1HTTKMT2A
SCHEMBL6565648 0.81 ELANE (0.48) ELANEKDM4EALDH1A1HTTMEN1
SCHEMBL6565945 0.81 ELANE (0.55) ELANEKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed