SCHEMBL6565700

SCHEMBL6565700

CC1=Cc2c(-c3ccccc3)cccc2C1[Ti](C)C.[SiH4]

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4060093 0.84 PDCD1 (0.33) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL8204575 0.82 PDCD1 (0.32) PDCD1CD274CHRNB2CHRNA4
SCHEMBL8203380 0.82 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4HTR1A
Hydrochloric Acid SCHEMBL7639321 0.81 PDCD1 (0.31) PDCD1CD274CHRNB2CHRNA4
SCHEMBL7625939 0.77 BCHE (0.33) PDCD1CD274
SCHEMBL5694274 0.77 PDCD1 (0.37) PDCD1CD274CHRNB2CHRNA4HTR1A
SCHEMBL7048688 0.76 PDCD1 (0.34) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL21778060 0.76 PDCD1 (0.34) PDCD1CD274CHRNB2CHRNA4HTR1A
SCHEMBL7525652 0.76 PDCD1 (0.36) PDCD1CD274CHRNB2CHRNA4HTR1A
SCHEMBL4603520 0.76 PDCD1 (0.36) PDCD1CD274CHRNB2CHRNA4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889911-A1 METALLOCENE COCATALYST THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP claimed
WO-1997036937-A1 METALLOCENE COCATALYST THE DOW CHEMICAL COMPANY (US) 1997-10-09 WO claimed
CN-110546171-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2023-02-28 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-110603274-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-09-30 CN disclosed
CN-110612315-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-26 CN disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
CN-108026115-B Multi-head or double-head composition capable of being used for chain shuttling and preparation method thereof 陶氏环球技术有限责任公司 2021-11-09 CN disclosed
CN-109937217-B Multi-or double-headed compositions suitable for chain shuttles and process for preparing same 陶氏环球技术有限责任公司 2021-09-14 CN disclosed
CN-112004818-A Silicon-terminated organometallic compounds and methods of making the same 陶氏环球技术有限责任公司 2020-11-27 CN disclosed
CN-111902439-A Binuclear olefin polymerization activator 陶氏环球技术有限责任公司 2020-11-06 CN disclosed
WO-2000034385-A1 MEL-BONDABLE POLYPROPYLENE/ETHYLENE POLYMER FIBER AND COMPOSITION FOR MAKING THE SAME THE DOW CHEMICAL COMPANY (US) 2000-06-15 WO disclosed
CN-1255928-A Catalyst system for high yield synthesis of polyolefins DOW CHEMICAL CO (US) 2000-06-07 CN disclosed
EP-0923609-A1 INCORPORATION OF FREE RADICAL INHIBITORS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1999-06-23 EP disclosed
EP-0898585-A1 POLYOLEFIN COMPOSITION WITH MOLECULAR WEIGHT MAXIMUM OCCURING IN THAT PART OF THE COMPOSITION THAT HAS THE HIGHEST COMONOMER CONTENT THE DOW CHEMICAL COMPANY (US) 1999-03-03 EP disclosed
EP-0891381-A1 OLEFIN SOLUTION POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1999-01-20 EP disclosed
WO-1998009995-A1 INCORPORATION OF FREE RADICAL INHIBITORS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1998-03-12 WO disclosed
WO-1997049738-A1 INCORPORATION OF FUNCTIONALIZED COMONOMERS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1997-12-31 WO disclosed
WO-1997044371-A1 POLYOLEFIN COMPOSITION WITH MOLECULAR WEIGHT MAXIMUM OCCURING IN THAT PART OF THE COMPOSITION THAT HAS THE HIGHEST COMONOMER CONTENT THE DOW CHEMICAL COMPANY (US) 1997-11-27 WO disclosed
WO-1997036942-A1 OLEFIN SOLUTION POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1997-10-09 WO disclosed