SCHEMBL6565730

SCHEMBL6565730

C=C(C)C(=O)NCc1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
MTNR1A P48039 2/20 0.55
CHRNB2 P17787 1/20 0.51
CHRNA4 P43681 1/20 0.51
ANPEP P15144 1/20 0.49
BCHE P06276 1/20 0.49
CA2 P00918 1/20 0.49
P2RX7 Q99572 1/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22323341 0.87 MEN1 (0.66) KMT2AMEN1MAPTMTNR1ACHRNB2
SCHEMBL1846496 0.86 MTNR1A (0.67) MTNR1A
SCHEMBL20824918 0.85 MEN1 (0.55) KMT2AMEN1MAPTMTNR1ACHRNB2
SCHEMBL59797 0.85 ALDH1A1 (0.47) KMT2AMEN1MAPTMTNR1A
SCHEMBL5999001 0.83 NQO2 (0.62) KMT2AMEN1MAPTMTNR1ACHRNB2
SCHEMBL4432071 0.82 KMT2A (0.65) KMT2AMEN1MAPTMTNR1ACHRNB2
SCHEMBL27623642 0.82 MAPT (0.40) KMT2AMEN1MAPTMTNR1A
SCHEMBL29145305 0.81 MTNR1A (0.62) KMT2AMEN1MAPTMTNR1ACHRNB2
SCHEMBL14844939 0.81 KMT2A (0.51) KMT2AMEN1MAPTMTNR1A
SCHEMBL5014444 0.80 MEN1 (0.62) KMT2AMEN1MAPTMTNR1ACHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 EP disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
EP-0667957-B1 SEPARATION MEDIA FOR ELECTROPHORESIS SOANE TECHNOLOGIES INC (US) 1998-01-28 EP disclosed
US-5569364-A CONTAINING GEL PARTICLES WHICH CAN BE SWOLLEN AND COLLAPSED BY SMALL CHANGES IN TEMPERATURE, PH, AND IONIC STRENGTH OF SOLVENT, THUS CHANGING VISCOSITY SOANE BIOSCIENCES, INC. (US) 1996-10-29 US disclosed
WO-1995030782-A1 SEPARATION MEDIA FOR USE IN GEL ELECTROPHORESIS SOANE BIOSCIENCES (US) 1995-11-16 WO disclosed
EP-0667957-A1 SEPARATION MEDIA FOR ELECTROPHORESIS SOANE TECHNOLOGIES INC. (US) 1995-08-23 EP disclosed
WO-1994010561-A1 SEPARATION MEDIA FOR ELECTROPHORESIS SOANE TECHNOLOGIES, INC. (US) 1994-05-11 WO disclosed