Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566442 | 0.90 | FNTA (0.47) | SLC6A9FNTAFNTBSLC6A4CNR1 | |
| SCHEMBL6826714 | 0.89 | SLC6A9 (0.48) | SLC6A9SLC6A4CNR1CNR2CYP2D6 | |
| SCHEMBL6566281 | 0.88 | SLC6A4 (0.55) | SLC6A9FNTAFNTBSLC6A4HTR1A | |
| SCHEMBL6259766 | 0.88 | SLC6A4 (0.50) | SLC6A9SLC6A4CNR1HTR1ACYP2D6 | |
| SCHEMBL6566500 | 0.88 | SLC6A9 (0.52) | SLC6A9SLC6A4CNR1GCGRCYP2D6 | |
| SCHEMBL6564361 | 0.85 | SLC6A2 (0.40) | SLC6A9SLC6A4CNR1CNR2GCGR | |
| SCHEMBL6754006 | 0.82 | SLC6A9 (0.44) | SLC6A9SLC6A4CNR1HTR1ACYP2D6 | |
| SCHEMBL6826663 | 0.82 | MTNR1B (0.45) | SLC6A9SLC6A4CNR1CASRCYP2D6 | |
| SCHEMBL6826945 | 0.81 | HPGD (0.50) | SLC6A9SLC6A4CNR2GCGRGAA | |
| SCHEMBL7054306 | 0.81 | KDM4E (0.44) | SLC6A4GCGRCYP2D6SLC6A2NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784299-B2 | CARBOCYCLIC ETHERS SUCH AS (METHYL-(3-(4-PHENOXY-PHENOXY)-3-PHENYL-PROPYL)-AMINO)-ACETIC ACID, USED AS NEUROTRANSMITTER ANTAGONISTS, FOR PROPHYLAXIS OF PSYCHOLOGICAL DISORDERS | PFIZER INC. | 2004-08-31 | — | — | US | disclosed |
| EP-1406861-A1 | SUBSTITUTED AROMATIC ETHERS AS INHIBITORS OF GLYCINE TRANSPORT | Pfizer Products Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030208081-A1 | Substituted aromatic ethers as inhibitors of glycine transport | PFIZER INC. | 2003-11-06 | — | — | US | disclosed |
| WO-2003000646-A1 | SUBSTITUTED AROMATIC ETHERS AS INHIBITORS OF GLYCINE TRANSPORT | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208081-A1 | Substituted aromatic ethers as inhibitors of glycine transport | SLC1A2, SLC1A1, SLC6A1 | SLC6A9 10/4885FNTA 790/4885FNTB 1368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.