⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182917 | 0.75 | — | — | |
| SCHEMBL9016905 | 0.69 | — | — | |
| SCHEMBL10864849 | 0.67 | — | — | |
| SCHEMBL29233409 | 0.67 | — | — | |
| SCHEMBL28739995 | 0.62 | — | — | |
| SCHEMBL18607532 | 0.62 | — | — | |
| SCHEMBL7111438 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL459761 | 0.58 | — | — | |
| SCHEMBL14446930 | 0.58 | — | — | |
| SCHEMBL17356129 | 0.58 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118056811-A | Method for preparing fluorine-containing nitrile compound by dehydrating amide compound | 浙江省化工研究院有限公司 | 2024-05-21 | — | — | CN | claimed |
| CN-118005535-A | Synthesis method of perfluoro-isobutyronitrile | 天津市长芦化工新材料有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-113683531-B | Method for preparing perfluoronitrile by pyrolysis and fluorination | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | claimed |
| CN-114085163-B | Method for synthesizing 2, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas phase catalytic fluorination | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | claimed |
| EP-3923301-B1 | GAS-INSULATED ELECTRICAL APPARATUS COMPRISING CARBON DIOXIDE, HEPTAFLUOROISOBUTYRONITRILE AND A HIGH CONTENT OF OXYGEN | GENERAL ELECTRIC TECHNOLOGY GMBH (CH) | 2022-09-07 | — | — | EP | claimed |
| CN-113683531-A | Method for preparing perfluoronitrile by pyrolysis fluorination | 化学与精细化工广东省实验室 | 2021-11-23 | — | — | CN | claimed |
| CN-118056811-A | Method for preparing fluorine-containing nitrile compound by dehydrating amide compound | 浙江省化工研究院有限公司 | 2024-05-21 | — | — | CN | disclosed |
| CN-118005535-A | Synthesis method of perfluoro-isobutyronitrile | 天津市长芦化工新材料有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005535-A | Synthesis method of perfluoro-isobutyronitrile | 天津市长芦化工新材料有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116693420-B | Method for preparing heptafluoroisobutyronitrile by liquid phase | 山东东岳化工有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-114014782-B | Method for preparing heptafluoroisobutyronitrile by amination-dehydration one-pot method in gas phase continuous mode | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | disclosed |
| CN-113683531-B | Method for preparing perfluoronitrile by pyrolysis and fluorination | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | disclosed |
| CN-114085163-B | Method for synthesizing 2, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas phase catalytic fluorination | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | disclosed |
| US-6521461-B2 | Contacting fluid containing fluoroalkene with ammonium hydroxide or nitrogen or sulfur or phosphorus containing nucleophile to form adduct | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-18 | — | — | US | disclosed |
| US-6437202-B2 | CONTACTING THE FLUOROALKENE WITH AMMONIUM HYDROXIDE OR A COMPOUND CONTAINING NITROGEN, SULFUR OR PHOSPHORUS TO FORM AN ADDUCT TO BIND TO A COATING OR ABSORBENT SUPPORT; REMOVAL OF PERFLUOROISOBUTYLENE FROM COOLANTS; MATERIALS HANDLING | 3M INNOVATIVE PROPERTIES COMPANY | 2002-08-20 | — | — | US | disclosed |
| US-20020063098-A1 | Fluoroalkene-nucleophile adducts for analysis and removal of fluoroalkenes | 3M INNOVATIVE PROPERTIES COMPANY | 2002-05-30 | — | — | US | disclosed |
| US-20010047117-A1 | Fluoroalkene-nucleophile adducts for analysis and removal of fluoroalkenes | 3M INNOVATIVE PROPERTIES COMPANY | 2001-11-29 | — | — | US | disclosed |
| EP-1114014-A1 | FLUOROALKENE-NUCLEOPHILE ADDUCTS FOR ANALYSIS AND REMOVAL OF FLUOROALKENES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6147268-A | CONTACTING FLUOROALKENE IN FLUID WITH MORPHOLINE TO FORM ADDUCT WHICH IS SUFFICIENTLY STABLE TO BE QUANTIFIED BY GAS CHROMATOGRAPHY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| WO-2000015588-A1 | FLUOROALKENE-NUCLEOPHILE ADDUCTS FOR ANALYSIS AND REMOVAL OF FLUOROALKENES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |