Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.47 |
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826663 | 0.87 | TUBB1 (0.45) | TUBB1PDE4BALDH1A1KDM4ETSHR | |
| SCHEMBL7418526 | 0.79 | ALDH1A1 (0.63) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL172939 | 0.78 | ALDH1A1 (0.71) | TUBB1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29392394 | 0.78 | ALDH1A1 (0.71) | TUBB1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6567753 | 0.78 | PTGS1 (0.48) | ALDH1A1TSHRPOLB | |
| SCHEMBL7387277 | 0.78 | KMT2A (0.47) | HIF1ATUBB1PDE4BPDE4APDE4C | |
| SCHEMBL2004982 | 0.76 | HRH3 (0.54) | ALDH1A1 | |
| SCHEMBL30826796 | 0.75 | ALDH1A1 (0.58) | ALDH1A1POLB | |
| SCHEMBL1665185 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NFE2L2KDM4ETDP1 | |
| SCHEMBL24750325 | 0.75 | ALDH1A1 (0.56) | HIF1APDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135360-B1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PF MEDICAMENT (FR) | 2004-03-31 | — | — | EP | disclosed |
| US-6350913-B1 | AROMATIC AMINE COMPOUNDS | PIERRE FABRE MEDICAMENT (FR) | 2002-02-26 | — | — | US | disclosed |
| EP-1135360-A1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032557-A1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2000-06-08 | — | — | WO | disclosed |