Pyrrole

Pyrrole

SCHEMBL6566537

N=C(N)N.c1cc[nH]c1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Pyrrole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biguanide SCHEMBL28181837 0.82
Pyrrole SCHEMBL27966815 0.81
Pyrrole SCHEMBL5142032 0.79
Pyrrole SCHEMBL29084184 0.79
Pyrrole SCHEMBL28916290 0.79
Pyrrole SCHEMBL28254862 0.77
Pyrrole SCHEMBL27473695 0.76
Pyrrole SCHEMBL1411959 0.76
Pyrrole SCHEMBL28814397 0.76 ALDH1A1 (0.40)
Pyrrole SCHEMBL16344858 0.76 ACHE (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114600285-A Electrochemically mediated gas capture including from low concentration streams 麻省理工学院 2022-06-07 CN disclosed
CN-114599443-A Electrochemical capture of lewis acid gases 麻省理工学院 2022-06-07 CN disclosed
CN-108463433-B Electrochemical process for gas separation 麻省理工学院 2022-04-26 CN disclosed
CN-103602986-B A kind of acidic etching liquid HOU YANHUI (CN) 2015-07-29 CN disclosed
CN-103614726-B A kind of engraving method HOU YANHUI (CN) 2015-07-29 CN disclosed
CN-103614726-A Etching method HOU YANHUI 2014-03-05 CN disclosed
CN-103602986-A Acidic etching liquid HOU YANHUI 2014-02-26 CN disclosed
CN-102154646-A acid etching liquid without generating chlorine and catalyst thereof YANHUI HOU 2011-08-17 CN disclosed
EP-1414440-A1 N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS Melacure Therapeutics AB (SE) 2004-05-06 EP disclosed
WO-2003068738-A1 PYRROLE DERIVATIVES AS LIGANDS OF MELANOCORTIN RECEPTORS NEUROCRINE BIOSCIENCES, INC. (US) 2003-08-21 WO disclosed
WO-2003013509-A1 N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTION LIGANDS MELACURE THERAPEUTICS AB (SE) 2003-02-20 WO disclosed