Pyrrole

Pyrrole

SCHEMBL28814397

N.NC(N)=O.c1cc[nH]c1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
OR51E2 Q9H255 1/20 0.40
CAPN1 P07384 1/20 0.33
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
THPO P40225 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrole SCHEMBL5142032 0.97
Pyrrole SCHEMBL711238 0.93 ALDH1A1 (0.40) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL27688372 0.93 ALDH1A1 (0.40) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL27461767 0.93 ALDH1A1 (0.40) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL28284015 0.93 LMNA (0.40) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL27477030 0.90 ALDH1A1 (0.38) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL16344858 0.87 ACHE (0.47) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL31319 0.87
Pyrrole SCHEMBL28823679 0.85 LMNA (0.33) ALDH1A1LMNATDP1OR51E2CAPN1
Pyrrole SCHEMBL28240858 0.85 ALDH1A1 (0.33) ALDH1A1LMNATDP1OR51E2CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104126597-B Promote plant growth promoter and its preparation method of balanced growth GUILIN GUIKAI BIOLOGICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) 2016-06-01 CN disclosed
CN-104126597-A Plant-growth promoter capable of promoting balanced growth and preparation method thereof GUILIN GUIKAI BIOLOG SCIENCE & TECHNOLOGY CO LTD 2014-11-05 CN disclosed