Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568009 | 0.81 | PTGDR2 (0.55) | ALDH1A1HIF1AMAPTNPSR1HTR2A | |
| SCHEMBL22419890 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6565669 | 0.79 | HTR2A (0.41) | ALDH1A1GAAKDM4EMAPTHTR2A | |
| SCHEMBL6564400 | 0.79 | PDK2 (0.47) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27842193 | 0.78 | ABCB1 (0.66) | ALDH1A1ABCB1KDM4E | |
| SCHEMBL6567847 | 0.78 | MAPT (0.44) | ALDH1A1ABCB1KDM4EMAPTNPSR1 | |
| SCHEMBL6564598 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTHTR2ASMN1; SMN2 | |
| SCHEMBL6567890 | 0.77 | CFD (0.46) | ALDH1A1GAAKDM4EHTR2A | |
| SCHEMBL6565808 | 0.76 | KMT2A (0.46) | ALDH1A1GAAXDHKDM4EMAPT | |
| SCHEMBL6564659 | 0.76 | ABCB1 (0.47) | ALDH1A1GAAABCB1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | ALDH1A1 907/4885GAA 3305/4885ABCB1 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.