Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22419890 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL6566640 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTHIF1ANPSR1SMN1; SMN2 | |
| SCHEMBL6565669 | 0.81 | HTR2A (0.41) | PTGDR2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8905331 | 0.79 | PTGDR2 (0.66) | PTGDR2MEN1KMT2AL3MBTL1GLA | |
| SCHEMBL6564598 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6567890 | 0.78 | CFD (0.46) | ALDH1A1TSHRLMNACYP2C9HTT | |
| SCHEMBL27482498 | 0.78 | BRD4 (0.49) | L3MBTL1ALDH1A1TSHRLMNATP53 | |
| SCHEMBL10816768 | 0.78 | PTGDR2 (0.60) | PTGDR2L3MBTL1GLATSHRTDP1 | |
| SCHEMBL7823764 | 0.78 | L3MBTL1 (0.64) | PTGDR2MEN1KMT2AL3MBTL1GLA | |
| SCHEMBL6565808 | 0.77 | KMT2A (0.46) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | PTGDR2 620/4885MEN1 4143/4885KMT2A 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.