Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566649 | 1.00 | TDP1 (0.45) | TDP1APPALOX5GAAPOLB | |
| SCHEMBL7899340 | 0.90 | POLB (0.47) | TDP1GAAPOLBCYP2C19RAB9A | |
| SCHEMBL7899338 | 0.90 | POLB (0.47) | TDP1GAAPOLBCYP2C19RAB9A | |
| SCHEMBL7905599 | 0.86 | SMN1; SMN2 (0.45) | RAB9AESRRGNPC1ALDH1A1TRPV1 | |
| SCHEMBL7905596 | 0.86 | SMN1; SMN2 (0.45) | RAB9AESRRGNPC1ALDH1A1TRPV1 | |
| SCHEMBL6567600 | 0.84 | ALDH1A1 (0.47) | TDP1GAAPOLBCYP2C19RAB9A | |
| SCHEMBL6567605 | 0.84 | ALDH1A1 (0.47) | TDP1GAAPOLBCYP2C19RAB9A | |
| SCHEMBL6568168 | 0.84 | TDP1 (0.45) | TDP1APPALOX5POLBRAB9A | |
| SCHEMBL6568165 | 0.84 | TDP1 (0.45) | TDP1APPALOX5POLBRAB9A | |
| SCHEMBL6568186 | 0.81 | LMNA (0.50) | TDP1RAB9AESRRGNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887336-B1 | Precursor compounds | GIVAUDAN SA (CH) | 2004-01-07 | — | — | EP | claimed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | claimed |
| EP-0887336-B1 | Precursor compounds | GIVAUDAN SA (CH) | 2004-01-07 | — | — | EP | disclosed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | disclosed |
| EP-0887336-A1 | Precursor Compounds | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-12-30 | — | — | EP | disclosed |