Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568165 | 1.00 | TDP1 (0.45) | TDP1APPALDH1A1L3MBTL1RAB9A | |
| SCHEMBL7899286 | 0.86 | CNR2 (0.39) | ALDH1A1L3MBTL1RAB9ACNR2NPC1 | |
| SCHEMBL7899283 | 0.86 | CNR2 (0.39) | ALDH1A1L3MBTL1RAB9ACNR2NPC1 | |
| SCHEMBL7905574 | 0.84 | CNR2 (0.49) | ALDH1A1L3MBTL1RAB9ACNR2EPHX1 | |
| SCHEMBL6566649 | 0.84 | TDP1 (0.45) | TDP1APPALDH1A1L3MBTL1RAB9A | |
| SCHEMBL6566655 | 0.84 | TDP1 (0.45) | TDP1APPALDH1A1L3MBTL1RAB9A | |
| SCHEMBL7907069 | 0.81 | MAPT (0.41) | ALDH1A1L3MBTL1RAB9ACNR2NPC1 | |
| SCHEMBL7907066 | 0.81 | MAPT (0.41) | ALDH1A1L3MBTL1RAB9ACNR2NPC1 | |
| SCHEMBL6569561 | 0.79 | ALOX15 (0.46) | TRPV1 | |
| SCHEMBL6569565 | 0.79 | ALOX15 (0.46) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887336-B1 | Precursor compounds | GIVAUDAN SA (CH) | 2004-01-07 | — | — | EP | claimed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | claimed |
| EP-0887336-B1 | Precursor compounds | GIVAUDAN SA (CH) | 2004-01-07 | — | — | EP | disclosed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | disclosed |
| EP-0887336-A1 | Precursor Compounds | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-12-30 | — | — | EP | disclosed |