Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605678 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL1677937 | 0.81 | GAA (0.64) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL15203335 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL4691652 | 0.79 | FPR1 (0.48) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL4745975 | 0.79 | NPC1 (0.48) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL14408269 | 0.78 | FPR1 (0.56) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL7150779 | 0.78 | HTT (0.63) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL8123656 | 0.77 | ALDH1A1 (0.51) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL4745979 | 0.76 | KDM1A (0.49) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL5440980 | 0.76 | KDM1A (0.49) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |