SCHEMBL656699

SCHEMBL656699

C=CCCCc1ccccc1C=C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.45
ALDH1A1 P00352 4/20 0.39
HPGD P15428 2/20 0.37
USP2 O75604 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HDAC1 Q13547 2/20 0.33
HDAC4 P56524 1/20 0.33
TSHR P16473 3/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
MITF O75030 1/20 0.31
EP300 Q09472 1/20 0.31
KAT2B Q92831 1/20 0.31
KAT5 Q92993 1/20 0.31
KAT8 Q9H7Z6 1/20 0.31
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
PTGER4 P35408 1/20 0.30
PTGER3 P43115 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9484248 0.92 ALDH1A1 (0.46) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL627744 0.88 ALDH1A1 (0.41) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL29724632 0.88 ALDH1A1 (0.41) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL31054112 0.87 ALDH1A1 (0.44) TLR8ALDH1A1TDP1TSHRLMNA
SCHEMBL6278153 0.87 ALDH1A1 (0.44) TLR8ALDH1A1TDP1TSHRLMNA
SCHEMBL6284419 0.87 ALDH1A1 (0.44) TLR8ALDH1A1TDP1TSHRLMNA
SCHEMBL6278186 0.85 ALDH1A1 (0.43) ALDH1A1HPGDUSP2TDP1TSHR
SCHEMBL6278393 0.85 ALDH1A1 (0.43) ALDH1A1HPGDUSP2TDP1TSHR
SCHEMBL6280633 0.85 ALDH1A1 (0.43) ALDH1A1HPGDUSP2TDP1TSHR
SCHEMBL6281460 0.85 ALDH1A1 (0.43) ALDH1A1HPGDUSP2TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150322186-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY PENN STATE RES FOUND (US) 2015-11-12 US claimed
US-9109057-B2 Methods and materials for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2015-08-18 US claimed
WO-2012024614-A2 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION (US) 2012-02-23 WO claimed
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2012-02-23 US claimed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
CN-108271378-B Polyolefin interpenetrating network material for hydrocarbon recovery 宾夕法尼亚州立大学研究基金会 2020-07-31 CN disclosed
EP-3350238-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY The Penn State Research Foundation (US) 2018-07-25 EP disclosed
CN-108271378-A Hydrocarbon recycling Polyvinyl Interpenetrating polymer Network material 宾夕法尼亚州立大学研究基金会 2018-07-10 CN disclosed
US-9861954-B2 Polyolefin interpenetrated network material for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2018-01-09 US disclosed
US-9688895-B2 Methods and materials for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2017-06-27 US disclosed
WO-2017048477-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION (US) 2017-03-23 WO disclosed
US-20170080404-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2017-03-23 US disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5608009-A OLEFIN-DIOLEFIN GRAFT POLYMER IDEMITSU KOSAN CO., LTD. (JP) 1997-03-04 US disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY LIPA, HSPH1, HPGDS TLR8 1468/4885ALDH1A1 3406/4885HPGD 38/4885
US-20170080404-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY PUF60, PARN, PARG TLR8 2567/4885ALDH1A1 4465/4885HPGD 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.