SCHEMBL6567157

SCHEMBL6567157

CCC(c1nc2ccc(OC(C)=O)cc2c(=O)o1)c1nc2ccc(OC(C)=O)cc2c(=O)o1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
POLB P06746 2/20 0.57
KDM4E B2RXH2 8/20 0.56
GAA P10253 4/20 0.56
MAPT P10636 2/20 0.56
CD74 P04233 1/20 0.55
MIF P14174 1/20 0.55
MEN1 O00255 2/20 0.52
HTT P42858 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 5/20 0.47
LMNA P02545 1/20 0.47
PKM P14618 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567413 0.84 KDM4E (0.54) KMT2APOLBKDM4EMAPTHTT
SCHEMBL6566018 0.83 SMN1; SMN2 (0.48) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6567154 0.82 KMT2A (0.52) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6563924 0.81 KMT2A (0.60) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6567556 0.81 ELANE (0.44) KMT2APOLBKDM4EGAAMEN1
SCHEMBL258516 0.80 KMT2A (0.62) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6565217 0.79 MAPT (0.47) KMT2AKDM4EMAPTMEN1HTT
SCHEMBL6565958 0.78 POLB (0.70) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6565611 0.77 ELANE (0.62) KMT2APOLBKDM4EMAPTMEN1
SCHEMBL6565631 0.77 KDM4E (0.43) KMT2APOLBKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed