SCHEMBL6565217

SCHEMBL6565217

CCC(c1nc2ccc(O)cc2c(=O)o1)c1nc2ccc(O)cc2c(=O)o1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
ESRRB O95718 1/20 0.43
ESRRA P11474 1/20 0.43
ELANE P08246 6/20 0.42
PDE2A O00408 1/20 0.41
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
HSD17B3 P37058 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565611 0.84 ELANE (0.62) MAPTKDM4EALDH1A1HTTMEN1
SCHEMBL6565334 0.82 KDM4E (0.47) KDM4EALDH1A1HTTELANE
SCHEMBL6565648 0.82 ELANE (0.48) MAPTKDM4EALDH1A1HTTMEN1
SCHEMBL6567397 0.82 ALDH1A1 (0.48) MAPTKDM4EALDH1A1HTTMEN1
SCHEMBL6567161 0.82 TP53 (0.51) MAPTKDM4EALDH1A1HTTMEN1
SCHEMBL6567556 0.82 ELANE (0.44) KDM4EALDH1A1HTTMEN1RAB9A
SCHEMBL6565631 0.81 KDM4E (0.43) MAPTKDM4EALDH1A1HTTMEN1
SCHEMBL6565065 0.80 KDM4E (0.45) KDM4EALDH1A1HTTELANE
SCHEMBL6567413 0.80 KDM4E (0.54) MAPTHSD17B10KDM4EALDH1A1HTT
SCHEMBL6565211 0.80 ELANE (0.49) MAPTHSD17B10KDM4EALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed