SCHEMBL6567154

SCHEMBL6567154

CC(=O)Oc1ccc2nc(CC(C)c3nc4ccc(OC(C)=O)cc4c(=O)o3)oc(=O)c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
POLB P06746 2/20 0.52
KDM4E B2RXH2 5/20 0.51
GAA P10253 3/20 0.51
MAPT P10636 2/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CD74 P04233 1/20 0.50
MIF P14174 1/20 0.50
MEN1 O00255 2/20 0.48
ELANE P08246 2/20 0.46
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
GLA P06280 3/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PKM P14618 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567412 0.86 ELANE (0.50) KMT2APOLBKDM4EMAPTHTT
SCHEMBL6566012 0.84 ELANE (0.48) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6563924 0.83 KMT2A (0.60) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6567552 0.83 ELANE (0.46) KMT2AKDM4EMAPTHTTSMN1; SMN2
SCHEMBL6567157 0.82 KMT2A (0.57) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6565211 0.81 ELANE (0.49) KMT2AKDM4EMAPTHTTMEN1
SCHEMBL6565609 0.80 ELANE (0.55) KMT2APOLBKDM4EGAAMAPT
SCHEMBL6567394 0.79 ELANE (0.49) KMT2AKDM4EHTTMEN1ELANE
SCHEMBL6565331 0.79 ELANE (0.49) KMT2AKDM4EHTTMEN1ELANE
SCHEMBL6567158 0.79 ELANE (0.49) KMT2APOLBKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed