Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052102 | 0.87 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9171594 | 0.86 | ALDH1A1 (0.46) | ALDH1A1 | |
| Silver SCHEMBL9171598 | 0.84 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL378661 | 0.76 | FGFR1 (0.30) | — | |
| SCHEMBL2188295 | 0.76 | PARP1 (0.39) | FLT3 | |
| SCHEMBL4066807 | 0.75 | HTT (0.46) | ALDH1A1 | |
| SCHEMBL8908207 | 0.74 | ALDH1A1 (0.30) | ALDH1A1ABL1PDGFRBKITBCR | |
| SCHEMBL5702764 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL2995564 | 0.73 | DPP4 (0.36) | ALDH1A1 | |
| SCHEMBL873880 | 0.73 | HSP90AA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446371-A1 | METHOD FOR THE PRODUCTION OF VINYL-ARENES, -HETEROARENES AND 1,3-DIENES FROM ARYL-, HETEROARYL- OR VINYL-CARBOXYLIC ACID DERIVATIVES | Studiengesellschaft Kohle mbH (DE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003043958-A1 | METHOD FOR THE PRODUCTION OF VINYL-ARENES, -HETEROARENES AND 1,3-DIENES FROM ARYL-, HETEROARYL- OR VINYL-CARBOXYLIC ACID DERIVATIVES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-05-30 | — | — | WO | disclosed |
| US-5672605-A | ADMINISTERING TO TREAT AUTOIMMUNE DISORDERS, TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 1997-09-30 | — | — | US | disclosed |
| US-5583139-A | Marcolide immunomodulators | ABBOTT LABORATORIES (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0729471-A1 | SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS | Abbott Laboratories (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5527907-A | IMMUNOSUPPRESSANTS | ABBOTT LABORATORIES (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1995014023-A1 | SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1995-05-26 | — | — | WO | disclosed |