Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.89 |
| ▸ | AGXT | P21549 | 6/20 | 0.89 |
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520782 | 0.94 | IDO1 (1.00) | IDO1AGXTMAOBTAAR1 | |
| Hydrochloric Acid SCHEMBL1716351 | 0.93 | IDO1 (1.00) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL6567303 | 0.82 | MAOB (0.64) | IDO1AGXTMAOBTAAR1ABCB1 | |
| SCHEMBL13263642 | 0.81 | MAOB (0.79) | IDO1AGXTMAOBABCB1HTR1A | |
| SCHEMBL1715197 | 0.81 | IDO1 (0.65) | IDO1AGXTMAOB | |
| Hydrochloric Acid SCHEMBL9716600 | 0.80 | IDO1 (0.66) | IDO1AGXTMAOB | |
| SCHEMBL3768643 | 0.79 | IDO1 (0.71) | IDO1AGXTMAOBTAAR1ABCB1 | |
| SCHEMBL31264 | 0.79 | IDO1 (0.71) | IDO1AGXTMAOBTAAR1ABCB1 | |
| SCHEMBL20469087 | 0.78 | IDO1 (1.00) | IDO1AGXT | |
| SCHEMBL7948 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404648-A1 | AMIDINE SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES WITH AN ANTITHROMBOTIC AND FACTOR XA INHIBITING ACTION | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003101942-A1 | AMIDINE SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES WITH AN ANTITHROMBOTIC AND FACTOR XA INHIBITING ACTION | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-12-11 | — | — | WO | disclosed |